Multi-Class Breast Cancer Histopathological Image Classification Using Multi-Scale Pooled Image Feature Representation (MPIFR) and One-Versus-One Support Vector Machines

نویسندگان

چکیده

Breast cancer (BC) is currently the most common form of diagnosed worldwide with an incidence estimated at 2.26 million in 2020. Additionally, BC leading cause death. Many subtypes breast exist distinct biological features and which respond differently to various treatment modalities have different clinical outcomes. To ensure that sufferers receive lifesaving patients-tailored early, it crucial accurately distinguish dangerous malignant (ductal carcinoma, lobular mucinous papillary carcinoma) tumors from adenosis, fibroadenoma, phyllodes tumor, tubular adenoma benign harmless subtypes. An excellent automated method for detecting desirable since doctors do not identify 10% 30% cancers during regular examinations. While several computerized methods classification been proposed, deep convolutional neural networks (DCNNs) demonstrated superior performance. In this work, we proposed ensemble four variants DCNNs combined support vector machines classifier classify histopathological images into eight classes: malignant. The utilizes power extract highly predictive multi-scale pooled image feature representation (MPIFR) resolutions (40×, 100×, 200×, 400×) are then classified using SVM. Eight pre-trained DCNN architectures (Inceptionv3, InceptionResNetv2, ResNet18, ResNet50, DenseNet201, EfficientNetb0, shuffleNet, SqueezeNet) were individually trained best-performing models (ResNet50, EfficientNetb0) was utilized extraction. One-versus-one SVM model 8-class classifier. Our work novel because while some prior has CNNs 2- 4-class classification, only one other a solution classification. A 6B-Net CNN utilized, achieving accuracy 90% rigorous evaluation, MPIFR achieved average 97.77%, 97.48% sensitivity, 98.45% precision on BreakHis dataset, outperforming state-of-the-art multi-class comprehensive set baseline models.

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ژورنال

عنوان ژورنال: Applied sciences

سال: 2022

ISSN: ['2076-3417']

DOI: https://doi.org/10.3390/app13010156